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Abstract

Due to its abundance and ubiquitous distribution in the natural environment, aluminium was not considered as a potential hazard for human health. However, harmful effects are reported in some occupational exposure and Alzheimer's disease. Recently, aluminium has been identified as a toxic agent causing dementia, osteomalacia, microcytic anaemia in patients affected with renal insufficiency, subjected to dialysis and oral ingestion of aluminium. The aluminium determination in environmental and biochemical samples became therefore of extreme interest. The aim of this work was to develop analytical procedures based on NAA and AAS for the determination of Al in chemicals used to prepare fluids, for dialysis (dextrose, NaCl, NaOH, NaHCO-3, Na-lactate, Na-acetate) as well as in commercial solutions for dialysis. Aluminium concentrations in the matrices mentioned could be very low (1-100 ppb). Many analytical difficulties are encountered because of contamination and loss of material, so that aluminium determination at sub-ppm levels requires great caution; collection, storage and sample treatment must be rigorously checked. NAA is a rapid, highly sensitive and suitable technique; however, the 27-Al (n, gamma) 28-Al thermal neutron activation is subject to serious interferences from the fast neutron induced reactions 31-P (n, alpha) 28-Al and 28- Si (n,p) 28-Al. In addition, and mostly in biological samples, the high 24-Na and 38-Cl induced activities make impossible the aluminium determination by INAA. In this work, NAA coupled to separation procedures either before or after irradiation was employed, along with flameless AAS.

Additional information

Authors: SPEZIALI M, CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG;DI CASA M, CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG;ORVINI E, CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG;MOUSTY F, CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG;PIETRA R, CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG;SABBIONI E, CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG;BERLIN A CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY), CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG;JRC ISPRA ESTAB. (ITALY), CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG;CEC LUXEMBOURG, CNR, CENTRE OF RADIOCHEMISTRY AND ACTIVATION ANALYSIS, UNIV. OF PAVIA (ITALY);JRC ISPRA ESTAB. (ITALY);CEC LUXEMBOURG
Bibliographic Reference: INTERNATIONAL SYMPOSIUM ON HEALTH EFFECTS AND INTERACTIONS OF ESSENTIAL AND TOXIC ELEMENTS, LUND (SWEDEN), JUNE 13-18, 1983 WRITE TO CEC LUXEMBOURG, DG XIII/A2, POB 1907 MENTIONING PAPER E 31752 ORA
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