Community Research and Development Information Service - CORDIS

Abstract

90-Sr, 89-Sr and 140-Ba appear in Mattauch's curve of uranium and plutonium fission in the maxima, e.g. in highest amounts together with the corresponding isobars to about 4.8 %, 5.9 % & 6.4 % in reactor burn-up as well as in fallout. These radionuclides are bone-seeking elements and therefore hazardous to man in the case of an accidental exposure. Little attention is paid at present to the fact, that there exists no sufficiently developed remedy in order to remove these nuclides, once incorporated into the human body. Previously cryptand (222) had been presented as a possible means to remove 90-Sr from mammals. Here cryptand (222) is presented as a means a more potent for the removal of barium-140 circulating in mammals. Parameters of pharmacological relevance, such as the dependency of the affinity of (222) towards 140-Ba, and of the (222)-dose as well as the therapeutic range are given. Decorporation of barium is also shown in the context of its relatives strontium and radium.

Additional information

Authors: MUELLER W H GESELLSCHAFT FUER STRAHLEN- UND UMWELTFORSCHUNG, NEUHERBERG (GERMANY), GESELLSCHAFT FUER STRAHLEN- UND UMWELTFORSCHUNG, NEUHERBERG (GERMANY)
Bibliographic Reference: 5TH INTERNATIONAL SYMPOSIUM TRACE ELEMENT METABOLISM IN MAN AND ANIMALS, ABERDEEN (SCOTLAND), JUNE 29-JULY 4, 1984 WRITE TO CEC LUXEMBOURG, DG XIII/A2, POB 1907 MENTIONING PAPER E 31513 ORA
Availability: Can be ordered online
Record Number: 1989123006100 / Last updated on: 1987-01-01
Category: PUBLICATION
Available languages: en