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Abstract

The effects of a single exposure to caesium gamma rays administered to rats at high dose rate have been observed on their spleen B lymphocyte populations. These effects increase with the dose as well as with the time, at least within the following ranges of experimental conditions: from 0 to 12 Gy and observation times of 1 and 3 days after irradiation. Doses less than or equal to 1.50 Gy lead to only a slight reduction of the B lymphocyte populations. On the contrary, doses equal to or greater than 3.50 Gy are extremely destructive for the spleen B lymphocytes. The non-circulating B lymphocyte population of the marginal zone compartment seems more susceptible to ionizing radiations than the circulating B lymphocyte population of the follicular compartment.

Additional information

Authors: BAZIN H, UNIVERSITE CATHOLIQUE DE LOUVAIN, UNITE D'IMMUNOLOGIE EXPERIMENTALE, BRUXELLES (BELGIUM);PLATTEAU B UNIVERSITE CATHOLIQUE DE LOUVAIN, UNITE D'IMMUNOLOGIE EXPERIMENTALE, BRUXELLES (BELGIUM), UNIVERSITE CATHOLIQUE DE LOUVAIN, UNITE D'IMMUNOLOGIE EXPERIMENTALE, BRUXELLES (BELGIUM)
Bibliographic Reference: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, VOL. 45 (1984), NO. 4, PP. 321-329
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