REPRODUCIBILITY ASPECTS IN SPECIFIC MIGRATION MEASUREMENTS - A COLLABORATIVE STUDY
Considerable variations in specific migration measurements are often observed when comparing results from different laboratories on apparently identical plastic - additive - liquid systems. In order to determine the influence of the various factors on reproducibility and repeatability in specific migration tests, and to develop an appropriate methodology, a collaborative study was undertaken with the participation of nine laboratories from the member countries of the EEC. Penta-erythryl - tetrakis-(3-(3,5-di-tert.butyl-hydroxyphenyl)-propionate) - further referred to as Irganox 1010 + and dihydroxybiphenyl (DHBP), were incorporated in high density polyethylene (HDPE). A water ethanol mixture, olive oil and a synthetic fat were selected as test liquids for contact with the plastics under well defined storage conditions. The study was carried out in four phases: (i) testing of a conventional h.p.l.c. method; (ii) testing and verification of a 14-C tracer technique; (iii) study of repeatability and reproducibility values in one-sided contact at constant temperature; (iv) investigation of the effect of storage conditions on repeatability and reproducibility criteria in one- and two-sided contact at two different temperatures. The collaborative exercise resulted in acceptable repeatability values for specific migration tests if storage conditions were accurately controlled.
Bibliographic Reference: FOOD ADDITIVES AND CONTAMINANTS, VOL. 1 (1984), NO. 1, PP. 53-61
Record Number: 1989123007500 / Last updated on: 1987-01-01
Available languages: en