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Abstract

Refined and advanced methods developed in the last few years rendered possible the use of mass spectrometry to analyze large biological molecules. These applications of mass spectrometry refer to the studies of natural polymeric compounds and non-polymeric substances with molecular weight above 1000. The chemical structure and the main physiological features of the different types of biopolymers, namely the polysaccharides, polyterpenes, nucleic acids and proteins are discussed with regard to possible applications of mass spectrometry measurements. Non polymeric macromolecules of biological origin, such as complex lipids, activated metabolites, large coenzymes and antibiotics, are briefly described and classified according to molecular size. The survey is intended as an introduction to the topic of natural macromolecules for a course on the use of mass spectrometry in the analysis of large biological substances.

Additional information

Authors: CAMPAGNARI F JRC ISPRA ESTAB. (ITALY), JRC ISPRA ESTAB. (ITALY)
Bibliographic Reference: IN "MASS SPECTROMETRY OF LARGE MOLECULES", 1985, PP. 1-34, BY ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM (THE NETHERLANDS)
Record Number: 1989124014600 / Last updated on: 1987-01-01
Category: PUBLICATION
Available languages: en