LYMPHOCYTE DISAPPEARANCE AND REAPPEARANCE AFTER A SINGLE WHOLE BODY IRRADIATION DOSE OF 5 GY
The effects of a single exposure to 5 Grays of caesium gamma rays administered at a high dose rate were investigated in rat lymphocyte populations. Such a dose completely depleted the B-cell population but never totally depleted the T-cell population. T and B lymphocytes reappeared in the spleen after 10-15 days and somewhat later in the mesenteric lymph nodes and Peyer's patches. In the spleen, non-circulating B lymphocytes of the marginal zone reappeared after a few days, as did the B lymphocytes of the follicles. Lymphoid tissues were observed to have recovered their normal aspect between days 50 and 60 after irradiation; however, even at that time, the germinal centres had not yet returned to normal.
Bibliographic Reference: ANN. INST. PASTEUR/IMMUNOL., VOL. 137 C (1986), PP. 313-328
Record Number: 1989125015600 / Last updated on: 1987-02-01
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