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Abstract

The potential role of neutron activation analysis is shown in the case of investigating the role of trace metals in relation with the occurrence of sarcoidosis trace metals in problems related to sarcoidosis. In particular, we report some cases of patients suspected to be affected by sarcoidosis but suffering in reality from lung diseases of occupational origin. NAA of lung specimens as well as BAL of these patients showed the simultaneous presence of obvious amount as cobalt, tungsten and tantalum and hence the hard metal origin of the observed fibrosis. It is most interesting that these metals were also found in blood, urine, hair and nails. This suggests that these biological specimens may be used as possible indicators of hard metal exposure while the hard metal origin of fibrosis in the case of suspected sarcoidosis can be excluded.

Additional information

Authors: PIETRA R, JRC-ISPRA;OSPEDALE NIGUARDA, MILANO, ITALY;EDEL J, JRC-ISPRA;OSPEDALE NIGUARDA, MILANO, ITALY;SABBIONI E, JRC-ISPRA;OSPEDALE NIGUARDA, MILANO, ITALY;RIZZATO G JRC-ISPRA, JRC-ISPRA;OSPEDALE NIGUARDA, MILANO, ITALY;OSPEDALE NIGUARDA, MILANO, ITALY, JRC-ISPRA;OSPEDALE NIGUARDA, MILANO, ITALY
Bibliographic Reference: XI WORLD CONGRESS ON SARCOIDOSIS AND OTHER GRANULOMATOUS DISORDERS, MILANO/I, SEPT. 6-11, 1987, AVAILABILITY: CEC-LUXEMBOURG, DG XIII/A2, BP 1907, MENTIONING PAPER ORA 33655 E
Availability: Can be ordered online
Record Number: 1989126064800 / Last updated on: 1989-05-01
Category: PUBLICATION
Available languages: en