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Although Quantitative Structure Activity Relationships (QSAR) methods may occasionally be misconceived as a magic tool which could - with the help of a computer and corresponding software programs - rapidly close the gaps in existing chemical, environmental and toxicological data files, a more critical approach cannot but reveal its utility in the application of validated models to environmental and ecotoxic risk assessment. If applied properly within the limits of validity and with expert judgement, considerable progress in the collection and screening of relevant chemical and toxicological data can be accomplished. In contrast, if applied improperly or indiscriminately, apparent results might be quite misleading. There is every prospect of a further expansion in the application of QSAR techniques, not only in increasing the number of validated models available and in improving their inherent predictive reliability, but also in finding a wider range of conscious and expert users. Much is to be gained if the overwhelming task of risk assessment of the multitude of existing and potentially hazardous chemicals can be addressed in a parallel and complementary manner.

Additional information

Authors: KARCHER W, JRC Ispra (IT);DEVILLERS J, CTIS, Ambérieu en Bugey (FR)
Bibliographic Reference: Paper presented: EURO-Course on Practical Applications of QSAR in Environmental Chemistry and Toxicology, Ispra (IT), June 11-15, 1990
Availability: Available from (1) as Paper EN 35386 ORA
Record Number: 199010858 / Last updated on: 1994-12-01
Original language: en
Available languages: en
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