How to correct for blanks in isotope dilution mass spectrometry
A general equation for isotope dilution mass spectrometry (IDMS) has been developed which considers the correction for blanks from labware and reagents used to dissolve, purify and transform samples in a form suitable for (thermal ionisation) mass spectrometric measurement. The equation takes into account that sample, spike and blank may have three different isotopic compositions. It is shown further that the isotopic composition of non-natural unknown samples must be determined independently on a sample of known chemical concentration, or, if this is not possible, on an aliquot of the unknown sample to be determined by IDMS.
Bibliographic Reference: Article: International Journal of Mass Spectrometry and Ion Processes, Vol. 104 (1991) pp. 45-48
Record Number: 199110516 / Last updated on: 1994-12-02
Original language: en
Available languages: en