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  • The development of reference methods in clinical chemistry : The contribution of the Community Bureau of Reference of the Commission of the European Communities


The use of reference method procedures in clinical chemical analysis is advocated by many experts as the most reliable approach to obtaining accurate results. The performance of such procedures must, however, be rigorous. This paper emphasises the importance of interlaboratory studies for this purpose. Examples are presented, taken from the work done under the BCR programme of the CEC. The determination of steroid hormones in serum by isotope dilution mass spectrometry and the measurement of enzyme catalytic activities, according to IFCC recommended methods, are discussed.

Additional information

Authors: COLINET E, CEC Bruxelles (BE)
Bibliographic Reference: Article: European Journal of Clinical Chemistry and Clinical Biochemistry, Vol. 29 (1991) pp. 237-240
Record Number: 199111166 / Last updated on: 1994-12-02
Original language: en
Available languages: en
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