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A review is given of the last 35 years of research on the toxicology, risk assessment and analytical chemistry of PCDDs, PCDFs and PCBs. The main conclusions are that: - Dioxins are extremely toxic for certain animals, but less toxic for humans. - Planar PCBs are toxicologically as important as dioxins. The combined risk assessment is facilitated by the toxicity equivalens concept. - The analytical chemistry of dioxins and PCBs has improved over the last 10 years through the coupling of HRGC and HRMS. By use of the isotope dilution technique, reliable measurements can be carried out at the low ppt level.

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Authors: LARSEN B, JRC Ispra (IT);JENSEN A A, Dansk Teknologisk Institut, Taastrup (DK)
Bibliographic Reference: Article: Dansk Kemi, Vol. 4 (1991) pp. 138-142
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