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  • Influence of chemical species on the determination of mercury in a biological matrix (cod muscle) using inductively coupled plasma mass spectrometry


An international exercise to certify the mercury content of a candidate reference material (Community Bureau of Reference, Certified Reference Material 422 Cod Muscle) has been performed. The analyte was determined using cold vapour atomic fluorescence spectrometry (CVAFS) and ICP-MS. In both cases, the sample digestion was achieved using a closed vessel microwave digestion procedure. The results obtained by ICP-MS using direct calibration against aqueous standards and internal standardisation were approximately half that obtained by CVAFS. Good agreement between the methods was obtained when standard additions and isotope dilution techniques were used, but only if spike addition was made before a cold nitric acid overnight digestion stage. Evidence suggests that the chemical species of the mercury present in the samples and standards influences the results obtained by ICP-MS. The results of the certification exercise for the mercury content of the material are briefly discussed.

Additional information

Authors: CAMPBELL M J, University of Ghent, Laboratory of Analytical Chemistry (BE);VERMEIR G, University of Ghent, Laboratory of Analytical Chemistry (BE);DAMS R, University of Ghent, Laboratory of Analytical Chemistry (BE);QUEVAUVILLER P, CEC Bruxelles (BE)
Bibliographic Reference: Article: Journal of Analytical Atomic Spectrometry, Vol. 7 (1992) pp. 617-621
Record Number: 199211201 / Last updated on: 1994-11-29
Original language: en
Available languages: en