Evaluation of dose components for the healthy tissue tolerance studies on dogs at the HFR, Petten
The paper summarises the results of investigating the effect of irradiating Beagle dog brain tissue at different blood B concentrations with an epithermal neutron beam before clinical trials of BNCT on glioma patients. The basic methodology used in the system is explained and a practical case is presented for one of the healthy tissue tolerance dogs. Doses, both physical and RBE weighted, were produced for pre-treatment planning studies. The principal objective of the work was to develop a computational model capable of evaluating the various dose components at all positions within a target volume from a predetermined neutron and photon source. The results are very promising and agreement with measured activation foils on the dogs or within phantoms is good.
Bibliographic Reference: Paper presented: 5th International Symposium on Neutron Capture Therapy for Cancer, Columbus (US), September 13-17, 1992
Availability: Available from (1) as Paper EN 36855 ORA
Record Number: 199310203 / Last updated on: 1994-11-29
Original language: en
Available languages: en