Community Research and Development Information Service - CORDIS

Abstract

The log-log relationship between the bioconcentration tendency of organic chemicals in fish and the n-octanol/water partition coefficients breaks down for very hydrophobic compounds. The use of parabolic and bilinear models allows this problem to be overcome. The QSAR equation log BCF = 0.910 log P - 1.975 log (6.8 x 1.0 E-7 P + 1) - 0.786 (n = 154; r = 0.950; s = 0.347; F = 463.51) was found to be a good predictor of bioconcentration in fish.

Additional information

Authors: BINTEIN S, CTIS, Lyon (FR);DEVILLERS J, CTIS, Lyon (FR);KARCHER W, JRC Ispra (IT)
Bibliographic Reference: Article: SAR and QSAR in Environmental Research, Vol. 1 (1993) pp. 29-39
Record Number: 199310593 / Last updated on: 1994-11-29
Category: PUBLICATION
Original language: en
Available languages: en