Isotope dilution mass spectrometry as a primary method of analysis
This paper discusses isotope dilution mass spectrometry (IDMS) as a measurement process. A definition of the isotope mass spectrometer (IMS) is given and an important difference between it and the IDMS procedure is highlighted. Major steps in the measurement process such as uncertainty assessment, the chemical preparation of a sample and the use of the internal ratio standard technique to correct errors are presented. The dynamic range of IDMS, which is particularly important in trace analysis, is also covered. The general IDMS equation is given and blank correction, which requires an extension of the IDMS equation, is discussed. The conclusions show that IDMS can be used over a very large dynamic range of concentrations.
Bibliographic Reference: Article: The Analyst, Vol. 30 (1993) pp. 328-333
Record Number: 199311447 / Last updated on: 1994-11-28
Original language: en
Available languages: en