Community Research and Development Information Service - CORDIS


This report deals with detailed methodologies in the development of the epidermal growth factor receptor (EGFR) assay, in relation to the incidence of EGFR-positivity in human breast cancer. To restrict the variation in EGFR-assay results between laboratories, it was decided to establish an efficient analytical method which gives reproducible results with high comparability between laboratories. The main aims of the research were to prepare the radioactive EGF-ligand and to establish a procedure to separate efficiently bound and free ligand.

Additional information

Authors: BENRAAD T J, Department of Experimental and Chemical Endocrinology, Faculty of Medicine, Nijmegen (NL);LEAKE R E, University of Glasgow, Department of Biochemistry (GB);FOEKENS J A, RRTI, Department of Biochemistry, Rotterdam (NL)
Bibliographic Reference: EUR 14799 EN (1993) 17 pp., MF, ECU 4
Availability: (2)
ISBN: ISBN 1 870965 12 4
Follow us on: RSS Facebook Twitter YouTube Managed by the EU Publications Office Top