Cytosolic 5'-nucleotidase/nucleoside phosphotransferase : A nucleoside analog activating enzyme?
This article describes the partial purification and characterisation of 5'-nucleotidase/phosphotransferase from cultured Chinese hamster lung fibroplasts (V79 cells). The cells have also been exposed to 8-azaguanine and 8-azaguanosine to compare the effect and activation pathway of base and nucleoside analogs. The role of cytosolic 5'-nucleotidase in the in vivo activation of 8-azaguanosine is discussed.
Bibliographic Reference: Article: Journal of Biochemical Toxicology, Vol. 9 (1994) No. 1, pp. 51-57
Record Number: 199410836 / Last updated on: 1994-11-28
Original language: en
Available languages: en