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Advances in electronics, computing, ion-optical design and vacuum technology have produced isotope mass spectrometers of impressive performance. Direct, high-accuracy determinations of the isotope abundances of most elements in isotopic certified reference materials (ICRMs) have become possible, and small instrumental and measurement errors have been largely eliminated through careful calibration protocols. Mass spectrometry through the IDMS technique is particularly valuable for elemental content determinations in both organic and inorganic analysis.

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Authors: DE BIEVRE P, JRC Geel (BE);DE LAETER J R, Curtin University of Technology, Department of Applied Physics, Perth (AU);PEISER H S, Rockville, Maryland (US);REED W P, National Institute of Standards and Technology, Maryland (US)
Bibliographic Reference: Article: Mass Spectrometry Reviews, Vol. 12 (1993) pp. 143-172
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