Community Research and Development Information Service - CORDIS


This book records presentations and discussions given at the European Commission/United States workshop on genetic risk assessment. The objective of the workshop was to identify the methodology, data requirements, and mechanistic research required to understand the human impact of germ cell mutagens. It focused on the feasibility of the Sobel parallelogram concept to estimate potential germ cell effects in humans. Four chemicals were selected for review at the meeting: ethylene oxide, 1,3-butadiene, acrylamide and cyclophosphamide. The first three are important industrial chemicals and the fourth, a commonly used cancer chemotherapeutic agent.

Additional information

Authors: RESEARCH AND EVALUATION ASSOCIATES INC., Research and Evaluation Associates Inc. (US)
Bibliographic Reference: EUR 15606 EN (1994) 439 pp., FS, free of charge
Availability: Available from Mr. Nolan, European Commission, DG XII, SDME 3/50, 200 rue de la Loi, B-1049 Bruxelles (BE)
ISBN: ISBN 92-826-4071-X
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