Community Research and Development Information Service - CORDIS


Laboratories all over Europe conduct chemical analyses in order to evaluate the quality of natural and commercial products, foodstuffs, the natural environment and the state of patients' health. This sometimes entails decisions that touch the whole of society. Measurements and the evaluation of the results of these must therefore meet a well-defined quality standard: that of correctness, accuracy and comparability. Within the field of chemical analysis, CRMs form an intermediate link between the quality of analysis results and their traceability to internationally accepted standards. After a general introduction to the subject, the production of CRMs is described (basic characteristics, requirements, specifications and feasibility studies). Specific examples of production discussed are control solutions as CRMs, CRMs and/or RMs of animal origin naturally contaminated with veterinary drug residues, and a CRM to characterise and standardise various C(18)-HPLC columns or phases from a wide range of commercial sources or batches. Issues of homogeneity, stability and accreditation are addressed; the remaining chapters deal with the applications and the producers of CRMs.

Additional information

Authors: BOENKE A, European Commission, Bruxelles (BE)
Bibliographic Reference: Article: Qualität im analytischen Labor (1995) pp. 135-157
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