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In the present work we are aiming to quantify the relationship between the stereoelectronic structure of benzo(a)pyrene, pyrene and phenanthrene quinones on their ability to induce chromosomal aberrations or oxidative stress.

The presented results infer the general conclusion that the genotoxic activity of studied quinones is an integrated effect of 2 reactivity mechanisms. The prevailing of one or the other of the mechanisms determines the qualitative difference between their toxic effects. .

Additional information

Authors: TURCHI G, JRC Ispra (IT);MEKENYAN O, University of Bulgaria, Department of PhysicalChemistry (BG);SBRANA L, University of Pisa (IT)
Bibliographic Reference: Paper presented: 15th International Symposium on Polycyclic Aromatic Compounds, Belgirate (IT), September 19-22, 1995
Availability: Available from (1) as Paper EN 39384 ORA
Record Number: 199512055 / Last updated on: 1996-01-15
Original language: en
Available languages: en