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A conference was held with expert presentations on the prediction of drug metabolism from preclinical studies, covering computational, in vitro and recombinant DNA approaches; genetic and nongenetic sources of interindividual and interethnic variability in drug metabolism, including probes for studies in vivo, induction and inhibition; and the identification of pharmacokinetic variability in drug metabolism and its management, including population approaches. The present and future impact of variability in drug metabolism on the pharmaceutical research and development processes was discussed.

Additional information

Authors: CEC, CEC Bruxelles (BE)
Bibliographic Reference: EUR 16479 EN (1995) 335pp., FS, free of charge
Availability: Available from the European Commission, Mr K Pithan, DG XII-B-1, 200 rue de la Loi, B-1049 Bruxelles (BE)
ISBN: 92-827-4386-1
Record Number: 199512149 / Last updated on: 1996-01-26
Original language: en
Available languages: en
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