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This paper presents an organized system for element specific sample collection and handling of human blood (whole blood, serum or plasma, packed cells or erythrocytes) and urine, also indicating a proper definition of the subject and sample. Harmonized procedures for collection, preparation, analysis and quality control are suggested. The aim is to assist scientists worldwide to produce comparable data which will be useful on a regional, national and international scale. The guidelines are directed to the elements aluminium, arsenic, cadmium, chromium, cobalt, copper, lead, lithium, manganese, mercury, nickel, selenium and zinc. These include the most important elements measured for their occupational or clinical significance, and serve as example of principles that will guide development of methods for other elements in the future.

Additional information

Authors: CORNELIS R, University of Gent, Laboratory of Analytical Chemistry (BE);HEINZOW B, Institutefor Environmental Toxicology of Schleswig-Holstein, Kiel (DE);HERBER R F M, University of Amsterdam, CoronalLaboratory for Occupational and Environmental Health (NL);MOLIN CHRISTENSEN J ETAL, National Institute for OccupationalHealth, Copenhagen (DK);SABBIONI E, JRC Ispra (IT);TEMPLETON D M, University of Toronto (CA);THOMASSEN Y, National Institute ofOccupational Health, Oslo (NO);YAHTER M, Karolinska Institute of Environmental Medicine, Stockholm (SE).;VESTERBERG O, National Institute of Occupational Health, Solna (SE)
Bibliographic Reference: Article: Pure and Applied Chemistry, Vol. 67 (1995) No. 8/9, pp. 1575-1608
Record Number: 199610043 / Last updated on: 1996-02-16
Original language: en
Available languages: en