Simultaneous determination of Co and Mn in urine by ETAAS. Method development using a simplex optimization approach
A fast method for the simultaneous determination of Co and Mn in urine was developed using a multielemental Perkin-Elmer SIMAA 6000 graphite furnace atomic absorption spectrophotometer. A Simplex optimization was used to establish the pyrolysis and the atomization temperature, and the ramp and hold time for the pyrolysis step. The sample preparation was a simple 1+1 dilution, using a diluent of 2% v/v HNO(3) and 0.05% m/v Triton X-100 in MilliQ-water. The experimental detection limits were 0.18 mg/l for Co, and 0.09 mg/l for Mn. The recovery studies, to check for bias, have shown acceptable accuracy for the procedure (104% for Co and 100% for Mn, with 15 and 13% RSD respectively).
Bibliographic Reference: Article: Journal of Analytical Atomic Spectrometry (1996)
Record Number: 199610380 / Last updated on: 1996-04-15
Original language: en
Available languages: en