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  • Review of trace elements in blood, serum and urine for the Czech and Slovak populations and critical evaluation of their possible use as reference values


The project Trace Element Reference Values in Human Tissues aims to establish and compare trace element reference values in tissues from inhabitants of the European countries as baseline values for clinical and toxicological assessment studies. In this context, one of the first steps considered is the critical evaluation of existing literature on trace element reference values in blood, serum and urine in the general population of each European country. This paper reviews the Czech and Slovak situation by assessing studies carried out in these countries for Al, As, Cd, Co, Cr, Cu, F, Mn, Hg, Ni, Pb, Rb, Sc, Se, V and Zn in blood, serum and urine. These studies show that most of the data available do not meet criteria designed recently for deriving reference intervals. Elements which present the highest potential risk for health in Czech and Slovak populations and for which reference values should be urgently established are: Cd, Hg, Pb As, Cr, Ni, Al, F, Mn, Tl V, Pt and essential trace elements such as I, Se and Zn for which a deficiency in Czech and Slovak populations was detected or is suspected.

Additional information

Authors: SABBIONI E, JRC Ispra (IT);VAN DER VENNE M T, CEC Luxembourg (LU);KUCERA J, Academy of Sciences of the Czech Republic, Nuclear Physics Institute, Rez near Prague (CZ);BENCKO V, Charles University, Institute of Hygiene and Epidemiology, Prague (CZ)
Bibliographic Reference: Article: The Science of the Total Environment, vol 166 (1995), pp. 211-234
Record Number: 199610539 / Last updated on: 1996-05-27
Original language: en
Available languages: en