The Challenge of Validation in Europe
Alternative methods which can reduce, refine or replace the use of laboratory animals in the testing of chemicals and products of many different kinds are badly needed, for scientific, logistic and economic reasons, as well as on humanitarian grounds. A symposium was held that focused on possibilities for meeting the terms of the Sixth amendment. Given the cooperation at all levels which is sought, it is possible to eliminate, within the next two years, the need for animals tests for the following: finished product safety, percutaneous absorption, phototoxicity, skin irritation, skin corrosion, mutagenicity and eye irritation. Furthermore, it is considered that a significant reduction in the need for animal tests for the following could be achieved within five years: sensitization, carcinogenicity, and reproductive toxicity. To meet this challenge, full cooperation is necessary, this being the key to success, not just for the European Centre for the Validation of Alternative Methods (ECVAM).
Bibliographic Reference: Paper presented: COLIPA Symposium on Alternatives to Animal Testing, Brussels (BE), November 25-30, 1995
Availability: Available from (1) as Paper EN 39636 ORA
Record Number: 199610613 / Last updated on: 1996-05-27
Original language: en
Available languages: en