Community Research and Development Information Service - CORDIS


In fulfilling its remit to coordinate the validation of alternative test methods at European Union level, the European Centre for the Validation of Alternative Methods (ECVAM) intends to conduct formal interlaboratory validation studies in accordance with the general principles laid down in the report of the CAAT/ERGATT workshop held in 1990, and the guidelines contained in the 1995 ECVAM/ERGATT workshop report. In addition, ECVAM is implementing a prevalidation scheme. This has been outlined in the first report of the ECVAM Task Force on Prevalidation, and includes 3 main phases: protocol refinement; protocol transfer; and protocol performance. The objective of the prevalidation process is to ensure that any method included in a formal validation study adequately fulfils the criteria defined for inclusion in such a study, so that financial and human resources are used more efficiently, and so that there is a greater likelihood that the expectations of those in the scientific, regulatory and animal welfare communities, who seek the replacement of current animal tests by relevant and reliable alternative methods, will be met.

Additional information

Authors: FENTEM J, JRC Ispra (IT);BALLS M, JRC Ispra (IT)
Bibliographic Reference: Paper presented: 2nd World Congress on Alternatives and Animal Use in the Life Sciences, Utrecht (NL), October 20-24, 1996
Availability: Available from (1) as Paper EN 39852 ORA
Record Number: 199611458 / Last updated on: 1997-01-16
Original language: en
Available languages: en