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Certified reference materials have a significant role to play in assuring quality of analytical measurements. They can be used to validate analytical procedures. Inorganic mass spectroscopy (IMS) is a very sensitive technique, which is crucial for many present day challenges in analytical chemistry. Mass spectrometry takes into account two important, often neglected characteristics: the particulate nature of matter as well as the existence of isotopic species. Because of this IMS will become increasingly important for reference materials and reference measurements.
A concise review is given of how different IMS techniques are currently being used in this particular domain. Because of the stringent reliability requirements in this field, the different calibration techniques are discussed, especially with respect to their inherent uncertainty.
The exact function of certified reference materials (CRM) and how traceable the certified values are, are discussed. One of the first initiatives of an official body in the integration of analytical chemical measurements has been to emphasize the role of primary methods of measurements. One method is isotope dilution, which in combination with mass spectrometry is considered to be an important tool in establishing traceability of analytical measurements. .

Additional information

Authors: TAYLOR P D P, JRC Geel (BE);DE BIÈVRE P, JRC Geel (BE)
Bibliographic Reference: Paper presented: 3 Symposium Massenspektrometrische Verfahren der Elementspurenanalyse, Jülich (DE), September 24-26, 1996
Availability: Available from (1) as Paper EN 39922 ORA
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