An evaluation of the applicability of high resolution ICP-mass spectrometry for isotope ratio measurements
The present paper reports on the capability of high resolution inductively coupled plasma mass spectrometry (HR-ICP-MS) for the accurate and precise determination of isotope ratios of which at least one of the isotopes involved is spectrally interfered when measured at low resolution, using Cu as a typical example. Careful selection of the measurement conditions allows a Cu-63/Cu-65 or Pb-206/Pb-207 isotope ratio precision of 0.1% (RSD for n = 10) at sufficiently high count rates (greater or equal to 100000 counts/s). In this work, Cu isotope ratios were determined in both an Antarctic sediment digest and in a human serum reference material. Although both isotopes involved were severely spectrally interfered when measured at low resolution, measurement at R = 3000 resulted in an isotope ratio that did not differ significantly from the expected natural isotopic abundance ratio. Finally, on the basis of the corresponding mass spectra at R = 3000, for both samples an attempt was made to identify the polyatomic ions that spectrally interfere with the Cu ion signals at low resolution.
Bibliographic Reference: Article: Analytical Chemistry (1997) University of North Carolina (US)
Record Number: 199611557 / Last updated on: 1997-01-27
Original language: en
Available languages: en