Electrochemical behaviour of a metallothionein related peptide in the presence of cadmium using cyclic voltammetry
The electrochemical study of the peptidic fragment Lys-Cys-Thr-Cys-Cys-Ala [56-61] MT I (FT) in the presence of cadmium was performed by cyclic voltammetry using a hanging mercury drop electrode in order to elucidate the diffusion-adsorption processes. The influence of scan range, number of cycles, scan rate and concentration were investigated. The variation of the initial and final potentials strongly modify the voltammetric features due to changes of concentrations of species near the electrode surface. For the first cycle, linear relationships were found between the peak current of the different peaks and the square root of the scan rate indicating that the electrochemical mechanism is mainly diffusion-controlled. Peak current as a function of the total concentration is also linear, at least for a given range of concentration. For concentrations of the mixture FT:Cd=1:1 higher than C approximately 3E-5 M, an adsorption pre-peak was detected during the cathodic scan. The electrochemical systems are reversible. The evolution of voltammograms was investigated for the sequential addition of cadmium to the peptidic fragment.
Bibliographic Reference: Article: Journal of Electroanalytical Chemistry
Record Number: 199810486 / Last updated on: 1998-05-05
Original language: en
Available languages: en