Community Research and Development Information Service - CORDIS


This is the report of the twenty-ninth of a series of workshops organized by the European centre for the validation of alternative methods (ECVAM). ECVAM's main goal is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures which would enable it to become well-informed about the state-of-the-art of non-animal test development and validation, and the potential for the possible incorporation of alternative tests into regulatory procedures. It was decided that this would be best achieved by the organization of ECVAM workshops on specific topics, at which small groups of invited experts would review the current status of various types of in vitro tests and their potential uses, and make recommendations about the best ways forward. The aims of this workshop were to find ways of reducing the number of animals used in biomedical research without reducing research output, and to make recommendations for practical ways in which this might be achieved.

Additional information

Authors: FESTING M F W, University of Leicester, MRC Toxicology Unit (GB);BAUMANS V, University of Utrecht, Department of Laboratory Animal Science (NL);COMBES R D, FRAME, Nottingham (GB);HALDER M, JRC Ispra (IT);HENDRIKSEN C F M, National Institute of Public Health and the Environment, Bilthoven (NL);HOWARD B R, University of Sheffield, Medical School, Field Laboratories (GB);LOVELL D P, BIBRA International, Carshalton (GB);MOORE G J, Pfizer Central Research, Sandwich (GB);OVEREND P, SmithKline Beecham Pharmaceuticals, Harlow (GB);WILSON M S, Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Harlow (GB)
Bibliographic Reference: Article: ATLA, Vol. 26 (1998) pp. 283-301
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