Community Research and Development Information Service - CORDIS

Abstract

There are several ongoing medical trials to use Bi-213 conjugated to monoclonal antibodies to kill tumor-cells of various cancer types. The institute is supplying Ac-225 generators for the test and is itself engaged in in-vitro cytotoxicity tests. The present supply of Ac-225 stems from Th-229 decay obtained from aged U-233. From possible alternative the reaction Ra-226 (p, 2n) Ac-225 is presently favoured. The fabrication of Ac-225 for Bi-213 generators will be described.

Additional information

Authors: KOCH L, JRC Karlsruhe (DE);APOSTOLIDIS C, JRC Karlsruhe (DE);JANSSENS W, JRC Karlsruhe (DE);MOLINET R, JRC Karlsruhe (DE);VAN GEEL J, JRC Karlsruhe (DE)
Bibliographic Reference: Paper presented: 13th Radiochemical Conference, Prague (CZ), April 19-24, 1998
Availability: Available from (1) as Paper EN 41716 ORA
Record Number: 199811245 / Last updated on: 1998-10-27
Category: PUBLICATION
Original language: en
Available languages: en