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Abstract

This article reports an evaluation of the proposed OECD testing strategy for skin irritation/corrosion as it relates to the classification of skin corrosives. By using a set of 60 chemicals, an assessment was made of the effect of applying three steps in the strategy, taken both individually and in sequence. The results indicate that chemicals can be classified as corrosive or non-corrosive with sufficient reliabilty by the sequential application of three alternative methods. For example, it does not appear necessary to measure acid/alkali reserve in addition to pH for the classification of pure chemicals.

Additional information

Authors: ECVAM, ;ISPRA (IT),
Bibliographic Reference: Article: Alternatives to Laboratory Animals, (1998) 709-720
Record Number: 199910681 / Last updated on: 1999-04-30
Category: PUBLICATION
Original language: en
Available languages: en
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