ECVAM 99/02 Drug Sensitivity of Granulocyte-macrophage precursors (CFU-GM) from fresh murine bone marrow and from long term bone marrow cultures
The granulocyte-macrophage colony forming unit assay has been widely used to investigate the pathogenic mechanism of drug-induced blood disorders and for screening the potential myelotoxicity of antineoplastics. Considering the wide use of this technique, there is a need for a more standardized protocol, particularly with respect to the exposure conditions. The sensitivity of granulocyte-macrophage progenitors to three antineoplastic drugs.
Bibliographic Reference: Article: Toxicology in Vitro, 12 (1998), 39-45
Record Number: 199910701 / Last updated on: 1999-05-14
Original language: en
Available languages: en