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Abstract

The institute for Reference Materials and Measurements and the International Federation for Clinical Chemistry and Laboratory Medicine (IFCC) characterized and certified a reference material under the name and number IRMM/IFCC-452. This report describes the certification of the catalytic concentration of gamma-glutamyltransferase (GGT) in a purified lyophilized material of porcine origin (kidney) in a bovine serum albumine matrix when measured by the IFCC recommended method at 37 degrees Celsius. The catalytic concentration of GGT in reconstituted material is certified to 114.2+/- 2.4 U/L or 1.90+/- 0.04 Ákat/L. It is the intention that the reference material should be used to control and optimize the performance of enzyme measurements, verify the comparability of results from different laboratories and be used as a reference material for manufacturers of reagents and diagnostic kits.

Additional information

Authors: CERIOTTI F ET AL, Reference Institute of Bioanalysis, Bonn (DE);SIEKMANN L, Deutsche Gesellschaft f³r Klinische Chemie e.V.;PAUWELS J, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);SCHIMMEL H, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);KRISTIANSEN N, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);LINSINGER T, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE)
Bibliographic Reference: EUR 19577 EN (2000) 10 pp.
Availability: Available free of charge from Documentation Service JRC Ispra
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