Community Research and Development Information Service - CORDIS


The main objective of the Action is to increase the knowledge of cellular and molecular aspects of normal and abnormal tooth formation and to make this information profitable for clinical work, including prevention, epidemiology, genetic counselling and therapeutics.

The secondary, derived, objectives range from more general, fundamental aspects to well focused specific problems:

- positive, constructive interaction of developmental biologists, comparative anatomists and paleontologists
- unravelling the molecular identity of neural crest derived dental cells
- resolving the mechanisms of their patterning in the developing jaws
- elucidating the nature of epithelial-mesenchymal signalling leading to tooth-specific histo-morphogenesis and eruption
- further characterisation of the phenotypes of dental papilla cells, odontoblasts, ameloblasts, cementoblasts, and the cells of the periodontium
- understanding of the control mechanisms involved in specific phenotypic expressions. essions.

Additional information

Authors: MANDENOFF A (EDITOR), COST Secretariat, CEC-DG XII/B1, Brussels (BE)
Bibliographic Reference: EUR 19205 EN (2000) 114 pp., EUR 17.50
Availability: Available from EUR-OP Sales agents
ISBN: ISBN 92-828-9465-7
Record Number: 200012796 / Last updated on: 2000-09-22
Original language: en
Available languages: en