Community Research and Development Information Service - CORDIS


The main objective of the Action is to increase the knowledge of cellular and molecular aspects of normal and abnormal tooth formation and to make this information profitable for clinical work including prevention, epidemiological, genetic counselling and therapeutics. The secondary, derived, objectives range from more general, fundamental aspects to well focused specific problems:

Positive, constructive interaction of developmental biologists, comparative anatomists and palaeontologists.

-Unravelling the molecular identity of neural crest derived dental cells.
-Resolving the mechanisms of their patterning in the developing jaws.
-Elucidating the nature of epithelial-mesenchymal signalling leading to tooth-specific histo-morphogenesis and eruption.
-Further characterization of the phenotypes of dental papilla cells, odontoblasts, ameloblasts, cementoblasts, and the cells of the periodontium.
-Understanding of the control mechanisms involved in specific phenotypic expressions.

Additional information

Bibliographic Reference: EUR 19205 EN (2000) 115pp, EUR: 17.50
Availability: Available from OOPEC L-2985 Luxembourg
ISBN: ISBN: 92-828-9465-7
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