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This summary of a report given at a conference describes the successful ECV AM study, which led to the scientific validation of three in vitro tests for embryotoxicity (rat whole-embryo culture, the micro-mass test, and the embryonic stem cell test.

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Authors: SPIELMANN H, ZEBET, BgVV, Berlin (DE);GENSCHOW E, ZEBET, BgVV, Berlin (DE);SCHOLZ G, ZEBET, BgVV, Berlin (DE);BROWN N, Department of Anatomy, St GeorgeÆs Medical School, University of London (UK);PIERSMA A, RIVM, Laboratory for Health Effects, Bilthoven (NL);BRADY M, AstraZeneca, Central Toxicology Laboratory, Macclesfield (UK);CLEMANN N, Novartis Pharma AG, Basel (CH);HUUSKONEN H, KTL, National Public Health Institute , Kuopio (FI);PAILLARD F, Sanofi-SynthÚlabo, SynthÚlabo Recherche, Gargenville (FR);BREMER S, ECVAM, Institute for Health and Consumer Protection, EC-JRC, Ispra (IT);BECKER K, Schering AG, Biological Development and Experimental Toxicology, Berlin (DE)
Bibliographic Reference: An article published in: ATLA 29. (2001) pp.301-303
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