Community Research and Development Information Service - CORDIS

Abstract

A high range and variety of cosmetic formulations that contain oxidative hair dyes and matrix-forming compounds have been industrially developed over recent years and are now available on the international market. Member states of the European Union are responsible for conducting analyses of cosmetic products as deemed necessary by law and European regulation enforcement. Therefore, inspection authorities as well as the cosmetics trade and industry need validated analytical methods for the identification, characterisation, and/or quality control of specific active ingredients or formulations with the aim of implementing the European Union Cosmetic Directives (76/768/ECC, 95/17/EC). In this frame, we validated a candidate reference method that enables the identification and quantification of hair dye-forming compounds. This method consists of a separation by RP-HPLC coupled with a DAD after a liquid-liquid extraction procedure for separating matrix components from the dye-forming compounds. The validation of the method includes common criteria such as the repeatability of the analysis and the establishment of figures of merit, as well as statistical evaluations and quality assurance in order to follow the recommendations of the Eurachem guide for analytical measurements.

Additional information

Authors: VINCENT U, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);BORDIN G, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);RODRÌGUEZ A R, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE)
Bibliographic Reference: An article published in: Journal of. Cosmetic Science, 53, (January/February 2002), pp.43-58
Follow us on: RSS Facebook Twitter YouTube Managed by the EU Publications Office Top