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  • European Union Risk Assessment Report. methyloxirane (propylene oxide). CAS No: 75-56-9, EINECS No: 200-879-2. Series: 2nd Priority List, Volume: 23


The report provides the comprehensive risk assessment of the substance methyloxirane (propylene oxide). It has been prepared by the United Kingdom in the frame of Council Regulation (EEC) No. 793/93 on the evaluation and control of the risks of existing substances.

The evaluation considers the emissions and the resulting exposure to the environment and the human populations in all life cycle steps. Following the exposure assessment, the environmental risk characterisation for each protection goal in the aquatic, terrestrial and atmospheric compartment has been determined. For human health the scenarios for occupational exposure, consumer exposure and humans exposed via the environment have been examined and the possible risks have been identified.

The human health risk assessment for methyloxirane (propylene oxide) concludes that there is at present concern for workers, consumers and humans exposed via the environment. The risk assessment concludes that a risk cannot be excluded as the substance is identified as a non-threshold carcinogen. The risks though are low and this should be taken into account when considering the feasibility and practicability of further specific risk reduction measures. The risk assessment for the environment concludes that there is at present no concern for the atmosphere, aquatic ecosystem, terrestrial ecosystem or for micro-organisms in the sewage treatment plant from sources of methyloxirane (propylene oxide) covered by Regulation 793/93.

The conclusions of this report will lead to risk reduction measures to be proposed by the Commission's Committee on risk reduction strategies set up in support of Council Regulation (EEC) 793/93.

Additional information

Authors: HANSEN B G ET AL (EDITORS), European Commission, Joint Research Centre, Institute for Health and Consumer Protection, European Chemicals Bureau, Ispra (IT)
Bibliographic Reference: EUR 20512 EN (2002), pp.138.
Availability: Available free of charge online at: A printed version of the report will later be available for sale from EUR-OP sales agents.
Record Number: 200215508 / Last updated on: 2002-11-12
Original language: en
Available languages: en