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Abstract

The Isotope Measurement (IM) unit of the Institute for Reference Materials and Measurements (IRMM) develops and performs reference measurements using primary methods, produces certified isotopic reference materials, and organises international measurement evaluation programmes. The IRMM-International Measurement Evaluation Programme (IMEP) is a programme for inter-laboratory comparisons (ILCs) that is open to all interested laboratories.

In July 1999, IRMM launched IMEP-17 as successor to IMEP-1, IMEP-4, IMEP-5 and IMEP-7, and decided to finance the production of two serum materials. These were ready and approved by the end of 2000. The increasing number of interlaboratory comparisons at higher metrological level during the 1990:s meant that it was now possible to include organic components in an IMEP comparison. Apart from the elements Ca, Cl, Cu, Fe, K, Li, Mg, Na, Se and Zn, also glucose, cholesterol, creatinine, urea, uric acid, thyroxine (T4), albumin, immunoglobuline G (IgG), amylase and g-glutamyl transferase (g-GT), were finally selected for IMEP-17.

The outcome of the certification campaign for IMEP-17 is summarised and the IMEP-17 reference values are also reported in units commonly used in routine laboratory medicine. The overall result for the twenty components is very satisfactory. It proves that NMIs and RMLs, in only a few years, have acquired sufficient competence with reference measurement procedures to support routine laboratories.

Tables in the report are the basis for the certificates that will be issued by IRMM as a product of this work. This report and the certificates will be distributed to all IMEP-17 co-ordinators and displayed on www.imep.ws

Additional information

Authors: ORNEMARK U, EQUALIS, Uppsala (SE);ÖRNEMARK U, EQUALIS, Uppsala (SE);ULDALL A, DEKS, Herlev University Hospital, Herlev (DK);VAN NEVEL L, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements (IRMM), Geel (BE);AREGBE Y, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements (IRMM), Geel (BE);TAYLOR P D P, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements (IRMM), Geel (BE)
Bibliographic Reference: EUR 20243 EN (2002), 37pp. Free of charge
Availability: Available from European Commission, JRC Knowledge Management Unit, Ispra (IT) Tel: +39 033278 9843 or +39 033278 9864 Fax: +39 033278 9623 E-mail: jrc-publications-office@ec.europa.eu
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