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The aim of this thesis was to evaluate the capability of different in vitro systems to compare metabolism of drugs and substrates by different polymorphic cytochrome P450 enzymes. The work was carried out at the European Commission, Joint Research Centre, and Institute for Health and Consumer Protection, ECVAM Unit, Ispra (IT).

Additional information

Authors: BOGNI A, School of Biology, University of Konstanz (DE)
Bibliographic Reference: Office for Official Publications of the EU, 2003. Reference: S.P.I.03.87. 80pp. Free of charge
Availability: Available from European Commission, JRC Knowledge Management Unit, Ispra (IT) Tel: +39 033278 9843 or +39 033278 9864 Fax: +39 033278 9623 E-mail:
ISBN: ISBN: 92-894-5290-8
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