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  • MEP-17, Trace and minor constituents in human serum, report to participants, Part 1: International comparability, Part 2: Methodology and quality specifications

Abstract

The International Measurement Evaluation Programme (IMEP) is a programme for interlaboratory comparisons. It is founded, owned and co-ordinated by the European Commission�s Institute for Reference Materials and Measurements (IRMM). The programme was established in 1988, in order to shed light on actual state of the practice in chemical amount measurements. Two facts made the programme known around the world.

IMEP aims to help build up confidence where trade or border crossing problems exists (between European countries or between Europe and elsewhere). Moreover, IMEP runs in support of European Commission (EC) policies (e.g. Consumer Protection and Public Health, Single Market, Environment, Research and Technology, External Trade and Economic Policy) and supports the chemical measurement systems of the European Union (EU) member states and pre-accession countries by providing assistance to the development of the national measurement systems.

Since 1988, IMEP has focused mainly on trace analysis in matrices, such as water, polyethylene, sediment, carbon dioxide, rice, car catalysts and serum. In July 1999 IRMM launched the IMEP-17, which focuses on twenty components in two human serum materials. The organisation of the interlaboratory comparison and the participants� results for serum Material 1 are the focus of this report.

Part 2 presents the participants� results for ten components in Material 2 (modified serum). Laboratory performance is displayed with Youden graphs. Special attention is paid to the performance of individual measurement procedures for creatinine, sodium and potassium. Analytical quality specifications, i.e. performance goals for routine analytical work is discussed and compared with the results in IMEP-17. The properties of the test materials are discussed from the point of view of commutability.

Additional information

Authors: VAN NEVEL L, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);SMEYERS P, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);HARPER C, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);TAYLOR P D P, European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (BE);ORNEMARK U, EQUALIS, Uppsala (SE)
Bibliographic Reference: EUR 20657 EN and EUR 20694 EN (2004), various paging. Free of charge
Availability: Available from European Commission, JRC Knowledge Management Unit, Ispra (IT) Tel: +39 033278 9893 Fax: +39 033278 5409 E-mail: jrc-publications-office@ec.europa.eu or Bruxelles (BE) Tel: +32 2 295 76 24 Fax: +32 2 299 63 22
Record Number: 200417571 / Last updated on: 2004-06-22
Category: PUBLICATION
Original language: en
Available languages: en
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