Community Research and Development Information Service - CORDIS

  • European Commission
  • CORDIS
  • Publications
  • Development of an Integrated Platform for Nanoparticle Analysis to verify their possible toxicity and the eco-toxicity (DIPNA) - Publishable Executive Summary
FP6

Development of an Integrated Platform for Nanoparticle Analysis to verify their possible toxicity and the eco-toxicity (DIPNA) - Publishable Executive Summary

Project ID: 32131
Funded under: FP6-NMP

Abstract

Nanotechnologies are the emergent technologies of the 21st century. Europe enjoys a strong position in nanosciences that is being translated into a growing competitiveness of the European industry. The fast growth of nanotechnologies is not paralleled by an equally fast evaluation of their impact on the environment and on animal and human health. Nanotechnological industries and activities generate nanoparticles (NP) that can be employed in an extensive variety of objects of everyday life (cloths, glasses, tiles, paper, etc.), thus they can represent an unprecedented type of pollution, a stimulus of unknown consequences for the living organisms. No information is available about the consequences of exposure to NPs on the functions of cells, tissues and organs, and their possible impact on health.
The aims of the DIPNA project are to provide knowledge about the impact of metallic and ceramic NPs on different types of cells, and to design assays and instruments for field analysis of nanotoxicology.
The DIPNA project addresses the NMP Research Area NMP-2004-3.4.1.5-2 "Interaction of engineered nanoparticles with the environment and the living world." The project aims at creating and validating instruments and assays, to assess the nanotoxicity of nanoparticles proposing new tests to verify their possible cytotoxicity and ways for detection of nanopollution in occupational sites, in order to promote prevention and nanosafety in NP manufacturing and handling. In this novel, multidisciplinary, multinational research project the Consortium aims at developing a precise knowledge on the impact of NP on human defence cells (nano-immunotoxicity). This knowledge will be validated in comparison with nanogenotoxicity and nano-carcinogenicity, i.e., studying in parallel the activity of NP in a standardized transformation assay in vitro, to predict the potential risks of exposure to NPs for human health.
The scientific knowledge gained during this project will provide the gr

Download application/pdf (39638)

Follow us on: RSS Facebook Twitter YouTube Managed by the EU Publications Office Top