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  • Towards new generations of neuro-implantable devices: engineering NEUROns/carbon NANOtubes integrated functional units (NEURONANO) - Publishable Executive Summary
FP6

Towards new generations of neuro-implantable devices: engineering NEUROns/carbon NANOtubes integrated functional units (NEURONANO) - Publishable Executive Summary

Project ID: 31847
Funded under: FP6-NMP

Abstract

The NEURONANO network proposes to integrate carbon nanotubes (CNT) with multielectrode array (MEA) technology to develop new generation biochips to help repair damaged central nervous system (CNS) tissues. Our approach is to push ahead the application and functionalization of carbon nanotubes in the CNS by focusing on CNT chemistry, peptide and surface chemistry and two complex networks in cultures: the brain (hippocampus and neocortex networks) and the spinal cord (locomotor networks).
We are specifically interested in understanding how the components underlying electrical activity are organized when implemented with conductive nano-substrates, and how this organization changes in the presence of molecular cues or chronic stimulations.
The research plan has three major aims: i) to answer fundamental questions about the biophysical interactions between nanomaterials and neurons ii) to exploit carbon nanotubes in the presentation of positive and negative cues, thus providing specific molecular environment to favour axonal regeneration and retargeting; iii) to develop the characterization of novel MEA/nanotube integrated devices, for multi-site extracellular stimulation and recording.

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Record Number: 9504 / Last updated on: 2008-10-30
Category: PRJS