Servizio Comunitario di Informazione in materia di Ricerca e Sviluppo - CORDIS

Biomedical applications of particle engineering

Colloidal particles have been surface modified with polymeric materials in order to optimize their targeting to defined body sites after injection. These sites include the general circulation, site of inflammation, tumours and endothelial cells. Particles injected subcutaneously are able to migrate to the regional lymph nodes in large quantities. The technology is applicable to colloidal carriers used for drug delivery, vaccines and diagnostic purposes.