Final Report Summary - HIP-LAB (High-throughput integrated photonic lab-on-a-DVD platforms)
The HIP-LAB project was focused on the monolithic integration of photonics and microfluidics on a biofunctionalized polymer DVD-shaped disk. To this effect, in an initial step, the photonic structure was optimized so as to require a single material to obtain both light confinement and controlled flow inside the disk (photonics on a disk), in a second step, the photonics was combined with centrifugal microfluidics (optofluidics on a disk), allowing handling and measuring complex liquid samples. Finally, the disk was functionalized (HIP-LAB disks) and, as a demonstrator, it was used to measure glucose in the physiological level. Important is to mention that, as opposite to the state of the art, the HIP-LAB disks can perform up to five simultaneous glucose measurements with very minute amount of sample, and with a response time of maximal two minutes, reducing thus both the number of false positive/negatives and the time-to-result.