Servizio Comunitario di Informazione in materia di Ricerca e Sviluppo - CORDIS

FP7

VISUAL-MS Report Summary

Project reference: 308115
Funded under: FP7-IDEAS-ERC

Mid-Term Report Summary - VISUAL-MS (Visualising Supramolecular Assembly by preparative Mass Spectrometry)

The progress of the VISUAL-MS project in the first half of its five-year duration has been excellent. A highly motivated, capable, and dynamic research team with complementary expertise and the right mix of junior and senior investigators, has been assembled. They are working on the development and construction of a new analytical instrument capable of depositing intact large (bio-)molecules onto atomically clean and flat surfaces and visualising them through the ultimate sub-nm spatial resolution of scanning probe microscopy. By enabling to apply ultrahigh resolution diagnostic techniques to essentially any type of complex functional molecule, this new instrument represents an essential step change in analytical capability and will open new horizons in the basic understanding of molecule-surface interactions and serve as a reference in the formulation of future rationale protocols for the fabrication of (bio)molecular functionalised substrates
Most of the initial planning phase has been completed and first very interesting and promising results have been obtained. These encompass technological and methodological achievements that originate from the planning and development parts of the project, and research achievements, resulting from solving specific fundamental scientific questions. In particular, new designs for the transport and soft-landing of molecular ions have been developed, original software applications for the efficient simulation and statistical analysis of ion trajectories have been created, and a state-of-the-art experimental setup equipped with a variable-temperature scanning tunnelling microscope has been fully designed and built. At the same time, exciting new results were produced while investigating the interaction of functional molecules with surfaces. In particular, it was showed that metallic surfaces can catalyse specific reactions on short peptides of the same type as those caused by the action of enzymes in biochemistry, while a new thin film growth mode was identified for molecular units with interesting applications in organic electronics and anticipated to occur for a wide class of metal-organic interfaces.

Contact

Cochrane, Catherine
Tel.: +44 27657 4453
E-mail
Record Number: 183358 / Last updated on: 2016-05-27
Information source: SESAM