Community Research and Development Information Service - CORDIS

Periodic Report Summary 1 - REDVA (Development of hemodynamic solutions in Renal Dialysis Venous Access Failure)

Successful haemodialysis (HD) requires regular access to the patient’s blood circulation. The three main methods of achieving renal dialysis vascular access (ReDVA) are arteriovenous fistula (AVF), arteriovenous graft (AVG) and central venous catheter (CVC). All three methods have strengths and weaknesses. All are limited by the formation of vessel narrowing (stenosis) due to venous intimal hyperplasia (VIH) that frequently leads to vascular access failure.
The ReDVA project is a joint industry-academia research programme which has focused on overcoming the scientific and technical barriers to the understanding, development and adoption of technologies to combat the significant clinical problem of vascular access failure in the haemodialysis population.
The aims of the ReDVA project are being achieved by utilising the expertise from each ReDVA centre, individually and collaboratively. UNIVDUN have examined current and novel pre- and post-surgical VA surveillance imaging techniques, and in collaboration with GU, they have investigated the use of contrast agents to enhance MRI surveillance. QEHB have studied novel and established surgical (AVF and AVG) and interventional techniques. They have also collaborated with GU to collate and compare the strengths and weaknesses of the numerous VA guidelines used worldwide. UL in collaboration with VFT and UNIVDUN have examined the haemodynamics (blood flow parameters) behind ReDVA which impact on VIH and VA patency. This study has utilised MRI images, flow rig models, and computation fluid dynamics (CFD).

Contact

Zoe Kidd, (Senior Finance Assistant)
Tel.: +44 1382 384047
E-mail

Subjects

Life Sciences
Record Number: 187454 / Last updated on: 2016-08-19
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