Community Research and Development Information Service - CORDIS

ERC

BRAINPOWER Report Summary

Project ID: 249670
Funded under: FP7-IDEAS-ERC
Country: United Kingdom

Final Report Summary - BRAINPOWER (Brain energy supply and the consequences of its failure)

This project established capillary pericytes as major regulators of brain blood flow, both physiologically and after ischaemia. This opens up new therapeutic possibilities for treating stroke, and suggests new concepts for the effects of ischaemia on non-brain tissues. It also discovered: a novel mechanism by which myelin is damaged in ischaemia and thus opens up new therapeutic possibilities for treating white matter ischaemia,novel signalling pathways controlling blood flow at the capillary and the arteriole level differentially, the relative magnitude of the energy supply from oxidative phosphorylation and glycolysis in brain slices, how synapses are optimised to maximise the information transmitted per energy used.

Contact

Michael Browne, (Head of European Research and Development)
Tel.: +44 020 3108 3120
Fax: +44 020 7813 2849
E-mail
Record Number: 189092 / Last updated on: 2016-09-15